Xiidra Versus Restasis: What is the Difference?

References: Ther Clin Risk Manag. 2013;9:409-15. doi: 10.2147/TCRM.S49754. Epub 2013 Oct 25. Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients. Stonecipher KG1, Chia J, Onyenwenyi A, Villanueva L, Hollander DA. Author information Abstract BACKGROUND: Dry eye is a multifactorial, symptomatic disease associated with ocular surface inflammation and tear film

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The Best Test to date for Lyme Disease: Recombinant VlsE of Borrelia garinii strain PBi displayed the highest sensitivity of all antigens tested for IgG detection and is also one of the most useful antigens for IgM. Due to its excellent sensitivity and specificity combined with ease of evaluation, this line immunoblot assay offers a useful improvement in serodiagnosis of Lyme borreliosis.

The Best Test to date for Lyme Disease What is the false positive rate of IgM p41 Western blot for Lyme? It is not clear & it is controversial. Some papers say even newborns can be born with a positive IgM p41. Who should we believe? For now, the below study seems to indicate there

The Best Test to date for Lyme Disease: Recombinant VlsE of Borrelia garinii strain PBi displayed the highest sensitivity of all antigens tested for IgG detection and is also one of the most useful antigens for IgM. Due to its excellent sensitivity and specificity combined with ease of evaluation, this line immunoblot assay offers a useful improvement in serodiagnosis of Lyme borreliosis. Read More »

Proof That Mesenchymal Stem Cells Help with Dry Eye and Other Disorders: Animal Studies

The study (Reference A) below show that a single injection of Bone Marrow Derived Mesenchymal Stem Cells (BMDMSC) improved the secretory function of the lacrimal gland in Sjögren’s syndrome-like diseased mice. This improved production of tears was most likely due to decreased inflammation and increased expression of the water channel aquaporin which is key in improving tear

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Best Lyme Disease Test: ELISA and then Western Blot but both together if there is a high suspicion given the high risk of false negative with ELISA

Best Lyme Disease Test Antibodies to Borrelia burgdorferi, the bacteria that causes Lyme Disease do not appear in the blood until several weeks (usually 4-6 weeks) after the tick bite. The Lyme bacteria are not always present in the blood. A patient could have been infected with a strain of Bb that is not covered

Best Lyme Disease Test: ELISA and then Western Blot but both together if there is a high suspicion given the high risk of false negative with ELISA Read More »

Meibomian Gland Stem Cell Injections (MeGSCI) or Stem Cell Injections into Meibomian Glands (STIM): More Risks on Stem Cell Injections

More Risks on Stem Cell Injections Many patients and their doctors are hoping against all hope that these stem cell injections will work. I too hope and pray these stem cell injections will work if injected into the meibomian gland. However, it has never been tried and there are still big concerns.  While we proceed

Meibomian Gland Stem Cell Injections (MeGSCI) or Stem Cell Injections into Meibomian Glands (STIM): More Risks on Stem Cell Injections Read More »

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