Cold Eeze, Excessive Zinc, and Dementia

Many know that I take a lot of Cold Eeze in the winter to prevent catching a cold. For the first time in years, no one got sick this winter at all. I usually don’t get sick and Cold Eeze decreases the time of being sick, but this was a shocking winter as no one even had a sniffle. 
For years, though, I have been worrried about the excess Zinc I take and the risk for Alzheimer’s. 
While this is not an exhaustive research dive into the literature, the study below seems to indicate more Zinc may be a good thing. 
Still one should not over do it on the Cold Eeze. So far I have limited my intake to 4 lozenges a day maximum for no more than 4 days. Check with your MD if you have any health issues before using more than what the directions recommend. 
Sandra Lora Cremers, MD, FACS 
BioMed Central

Zinc and the aging brain

Johnathan R. Nuttall and Patricia I. Oteiza

Additional article information


Alterations in trace element homeostasis could be involved in the pathology of dementia, and in particular of Alzheimer’s disease (AD). Zinc is a structural or functional component of many proteins, being involved in numerous and relevant physiological functions. Zinc homeostasis is affected in the elderly, and current evidence points to alterations in the cellular and systemic distribution of zinc in AD. Although the association of zinc and other metals with AD pathology remains unclear, therapeutic approaches designed to restore trace element homeostasis are being tested in clinical trials. Not only could zinc supplementation potentially benefit individuals with AD, but zinc supplementation also improves glycemic control in the elderly suffering from diabetes mellitus. However, the findings that select genetic polymorphisms may alter an individual’s zinc intake requirements should be taken into consideration when planning zinc supplementation. This review will focus on current knowledge regarding pathological and protective mechanisms involving brain zinc in AD to highlight areas where future research may enable development of new and improved therapies.

Keywords: Zinc, Aging brain, Alzheimer’s disease, Diabetes, Nutrigenomics
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