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Low Carbohydrate and Diet with a Low Glycemic Index Potentially Improves Retinal Blood Vessel Health

October 21, 2016
Low Carbohydrate and Diet with a Low Glycemic Index Potentially Improves Retinal Blood Vessel Health
Nutr J. 2016 Oct 18;15(1):88.

Dietary glycemic index and retinal microvasculature in adults: a cross-sectional study.

Sanchez-Aguadero N1,2, Alonso-Dominguez R3, Recio-Rodriguez JI4, Patino-Alonso MC5, Gomez-Marcos MA6, Martin-Cantera C7, Schmolling-Guinovart Y8, Garcia-Ortiz L9; EVIDENT II Group.

Author information

Abstract

OBJECTIVE:

To analyze the relationship between dietary glycemic index (GI) and retinal microvasculature in adults.

METHODS:

This was a cross-sectional study of 300 subjects from the EVIDENT II study. Dietary GI was calculated using a validated, semi-quantitative food frequency questionnaire. Retinal photographs were digitized, temporal vessels were measured in an area 0.5-1 disc diameter from the optic disc and arteriolar-venular index (AVI) was estimated with semi-automated software.

RESULTS:

AVI showed a significant difference between the tertiles of GI, after adjusting for potential confounders. The lowest AVI values were observed among subjects in the highest tertile of GI, whereas the greatest were found among those in the lowest tertile (estimated marginal mean of 0.738 vs. 0.768, p = 0.014).

CONCLUSIONS:

In adults, high dietary GI implies lowering AVI values regardless of age, gender and other confounding variables.


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