Rare risk with chronic carbamazepine

Rare risk with chronic carbamazepine:

. 2016 Oct; 3: 31–33.
Published online 2016 May 28. doi:  10.1016/j.ajoc.2016.04.010
PMCID: PMC5757391
PMID: 29503903

Pediatric conjunctival lymphoma associated with oral carbamazepine use

Abstract

PURPOSE:

To report a case of a pediatric patient diagnosed with conjunctival lymphoma associated with oral carbamazepine use.

OBSERVATION:

An 11-year-old boy who presented with 5-month history of a small nasal conjunctival mass in the left eye that failed therapy with topical corticosteroids. Upon excision and molecular analysis, diagnosis of Follicular Lymphoma was favored. The patient was healthy and did not have any known risk factors except for a history of epilepsy treated with systemic carbamazepine.

CONCLUSION AND IMPORTANCE:

We report a case of a rare childhood conjunctival lymphoma. Conjunctival lymphomas may masquerade as chronic conjunctivitis, or scleritis that fail therapy with topical corticosteroids. Furthermore, our patient did not have any known risk factors such as old age, systemic lymphoma or immunosuppression. The patient did have a history long-term use of systemic carbamazepine. This is to our knowledge the first case conjunctival lymphoma that may be associated to the use of carbamazepine.
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