Still only available abroad (like Japan: see below), Rebamipide show promise in helping relieve patient’s dry eye symptoms. We are investigating how to formulate a drop from the FDA approved systemic medication via the NIH currently. Best regards, Sandra Lora Cremers, MD, FACS Rebamipide ophthalmic suspension for the treatment of dry eye syndrome: a critical […]
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Eye pain, chronic tearing, eye redness, itchiness, and acute & chronic dry eye can sometimes be due to a very common malady: clogged meibomian glands. These glands are located at the base of each eyelash. There are approximately 50 glands on the upper eyelids and 25 glands on the lower eyelids. The oily substance produced
Tea Tree Oil & Cliradex instructions I have been prescribing Tea Tree Oil (TTO) for my patients, friends, and family members who have dry eye symptoms, foreign body sensation, irritation, chronic burning, rosacea, ocular rosacea. Tea Tree Oil comes from Australia from the Tea Tree Oil plant, though some companies have created a version of
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There has been a good deal of research looking into the effect of Epigallocatechin gallate (EGCG), which is present in green tea, on dry eyes. EGCG has been shown to decrease angiogenesis and inflammation and a paper published by a friend Dr. Reza Dana at Harvard Medical School shows this effect on mice (see below).
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Cornea. 2012 Nov;31(11):1313-8. doi: 10.1097/ICO.0b013e3182542085. Stability of serum eye drops after storage of 6 months. Fischer KR, Opitz A, Böeck M, Geerling G. Source Department of Periodontology, University of Wuerzburg, Wuerzburg, Germany. Abstract PURPOSE: Serum eye drops are used for the treatment of ocular surface disease (eg, Sicca syndrome). The objective of this experimental study was to investigate whether they maintain their wound-healing potency
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Autologous Serum Eye Drops are very effective, but all patients need to be aware of potential risk of contamination with fungi and bacteria. Cornea. 2013 Aug;32(8):1116-9. doi: 10.1097/ICO.0b013e3182910036. Contamination risk of 100% autologous serum eye drops in management of ocular surface diseases. Thanathanee O, Phanphruk W, Anutarapongpan O, Romphruk A, Suwan-Apichon O. Source *Department of Ophthalmology, Faculty of Medicine, and †Blood Bank Unit, Srinagarind
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The below has the potential to revolutionize the way eye surgeons evaluate the meibomian glands in relation to dry eye complaints. Right now, we mostly use subjective assessments of the meibomian glands and their overall function. (Unfortunately, there are still eyeMDs, who do not have time to do a thorough examination of the meibomian glands
Ophthalmology. 2013 Jun;120(6):1158-65. doi: 10.1016/j.ophtha.2012.12.022. Epub 2013 Mar 13. A Randomized, Multicenter Phase 3 Study Comparing 2% Rebamipide (OPC-12759) with 0.1% Sodium Hyaluronate in the Treatment of Dry Eye. Kinoshita S, Oshiden K, Awamura S, Suzuki H, Nakamichi N, Yokoi N; Rebamipide Ophthalmic Suspension Phase 3 Study Group. Source Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. Electronic address: shigeruk@koto.kpu-m.ac.jp.
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Meibomian Gland Probing The Meibomian Gland has been hidden from the sight of patients and doctors alike for too long. When I was a resident at New York Eye and Ear Infirmary in 2000, one of our attendings wound not infrequently come to the Emergency Room often at odd hours asking us to take a
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New Frontiers in Dry Eye Treatments: As new treatments enter the marketplace, clinical practice patterns are still being optimized. Future head-to-head studies will clarify the optimal method for treatment, number of treatments, frequency intervals of these new exciting options. Currently, we are beginning a head to head study at Visionary Ophthalmology to see which of
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