My patients are very smart and educated. Many have told me of their frustration in finding eye surgeons who take dry eyes symptoms and eye pain seriously and knows about all the treatment option to help them with their symptoms.
The focus for ophthalmologists, at least, has long been eye surgery which takes years to master. In residency, the most I learned about dry eye was related to eyelid/eye anatomy, the term blepharitis which was thought only to be do to Staph aureus (the word Demodex was never mentioned), and the use of artificial tears (Restasis was not mentioned; meibography was not even an idea yet in people’s minds that I knew of).
Fast forward 20 years, many of my patients have done a great deal of research to educate themselves and the doctors who treat them. The area of dry eye research and treatments has sky-rocketed to the point that it is hard for the average surgeon to keep track of all options, even if they read key ophthalmology journals, like I do.
Thymosin Beta 4 is a perfect example. This paper was published in 2013, 2015, & 2018 but phase 4 trials are only beginning on this potential treatment. Will it pass FDA criteria: we are waiting to find out.