A dear friend has a new gout attack so am looking up the latest in prevention and treatment.
1. Gout is an inflammatory arthritis due to deposition of monosodium urate crystals.
2. It is associated with hyperuricemia: aserum urate level of 6.8mg per decilitre (404micromol per liter) or more
3. Approximate US prevalence: estimated at 3.9% of adults (~8.3 million people).
4. Treatments for acute attack include:
A. NSAIDS nonsteroidal anti-inflammatory drugs
B. colchicines: allopurinol is cheap and effective
C. glucocorticoids and possibly corticotrophin: many risks
D. New treatment option:
E. PRP is an emerging treatment but 1 case report of PRP injection making gout attack. for a variety of musculoskeletal disorders involving ligament bone joint and muscles. It had been studied in conditions such as cruciate
When uric acid, the end product of purines metabolism, rises above 6.8 mg/dL in peripheral blood, urate sediments can form within tissues.